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Adju-Phos®

Adju-Phos is a range of aluminium phosphate gel products which have been specifically developed for use as an adjuvant in vaccines. The gel is a suspension of hydrated amorphous aluminium hydroxyphosphate nano/micron size crystal in loose aggregates. Adju-Phos products have a net negative charge at neutral pH and effectively adsorb positively charged antigens. The primary purpose of the adjuvant in vaccines is to boost the antibody-mediated (Th2) immune response to the antigens. Adju-Phos products can be combined with other adjuvant types (such as monophosphoryl lipids) to achieve a balanced Th1/Th2 immune response. Adju-Phos is supplied in two variants with pH-values at ca. 6.5 and at ca. 5.0. Both variants contain 0.9% NaCl (saline) to reduce injection site discomfort. Adju-Phos is produced in classified clean rooms to prevent contamination, sterilised and aseptically filled in a grade A clean room.
Adju-Phos®
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Croda Denmark | Vaccine Adjuvants

Over 80 years of trusted adjuvant supply

Product details

Chemical group

  • Aluminium hydroxyphosphate

Administration route

  • Vaccine adjuvant

Market application

  • Human vaccines
  • Veterinary vaccines

Functions

  • Vaccine adjuvant

Physical form

  • A gel-like aqueous suspension. A supernatant forms when the product is left idle.
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