Our excipient portfolio for liquid oral medicines includes high purity pharmaceutical solubilisers, emulsifiers, active pharmaceutical ingredient (API) stability enhancers and self-emulsifying (SEDDS) and self-microemulsifying drug delivery systems (SMEDDS). SEDDS and SMEDDS improve the oral bioavailability of poorly water soluble oral drugs, typically found in BCS Class II of the Biopharmaceutics Classification System.
The taste of oral liquid medicines can be unpleasantly affected by the presence of excipients. Super Refined™ excipients have minimal taste compared to their standard pharmaceutical equivalent grades, resulting in more palatable patient medicines.
To demonstrate this, our Super Refined excipients and their standard pharmaceutical equivalent grades were tested by a panel of trained taste specialists (Sensory Spectrum, Inc.) to quantitatively identify the degree of difference in taste. The Degree of Difference (DOD) scores ranged from 0-10, with 0 indicating no difference and 10 indicating an extreme difference. A DOD of 5 or higher indicates that consumers will be able to perceive a difference in taste, while a DOD of 4-5 indicates a consumer might perceive a difference in taste.