Super Refined™ Crodamol™ IPM
Chemical Description
Isopropyl Myristate
Product Description
Highly purified grade of isopropyl myristate for use with sensitive active pharmaceutical ingredients or in applications where standard Crodamol IPM is not suitable. The proprietary Super Refining process removes polar impurities without altering the chemical composition of the excipient. This reduces the potential for adverse interactions between the excipient and the API, enhancing active stability and efficacy. Super Refined Crodamol IPM is a lipophilic enhancer that promotes skin penetration by means of bilayer disruption and disordering. It assists the percutaneous absorption of water-soluble and oil-soluble drugs by means of partial leaching of the epidermal lipids. The bilayer architecture of the stratum corneum lipids is disorganised by the introduction of phase separation and direct disruption of a proper lamellar arrangement. This results in the improvement of the skin’s reception for transdermal and transfollicular penetration.
Pharmacopoeia Compliance
- FDAIIG Listed
- JP
- PhEur
- USP/NF
Chemical Group
- Ester
Market Application
- Human Pharmaceutical
- Veterinary Health
Functions
- Emollient
- Self-emulsifying drug delivery
Administration Route
- Auricular
- Nasal
- Ophthalmic
- Topical
Typical Properties
Physical Form
- Colourless liquid
Literature
Chromatographically Purified Excipients Stability Enhancement and Topical Delivery of Benzocaine
Language: English | Type: Poster
Enhancing Penetration of Topical Actives
Language: English | Type: Product Overview Sheets
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