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Crodafos™ CES

Chemical Description

Cetearyl Alcohol (and) Dicetyl Phosphate (and) Ceteth-10 Phosphate

Product Description

Phosphate-based emulsifying and conditioning wax that produces stable thixotropic O/W emulsions, allowing rapid active release and localised delivery of active to the skin. The formation of lamellar liquid crystal oleosomes mean that Crodafos CES-based emulsions offer greater versatility compared to more conventional phosphate-based emulsifiers, enabling formulators to create a wide range of elegant and efficacious products that are both cost-effective as well as functional. They exhibit a combination of natural substantivity, greater oil deposition, and shear thinning properties promoting fast targeted release of both oil and water-based actives. Recommended topical usage levels of 5-8%.

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Chemical Group
  • Emulsifying wax
Market Application
  • Dermatology
Functions
  • Anionic surfactant
  • Emulsifier
Administration Route
  • Topical
Typical Properties
Physical Form
  • White pastilles m.p. 51-58ºC
Literature

Crodafos CES

Language: Portuguese | Type: Data Sheet | Size: 150kb

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Crodafos CES

Language: Spanish | Type: Data Sheet | Size: 272kb

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Percutaneous Absorption of Skin Actives via a Novel Excipient

Hydrocortisone is a widely prescribed topical agent, easily penetrates the skin, long term exposure may cause skin atropy. Reducing the rate of systemic absorption would provide new treatment options for skin diseases and conditions.

Language: English | Type: Poster | Size: 1133.73kb

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Topical Dosage Form Excipients

Language: Portuguese | Type: Data Sheet | Size: 519kb

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FDA Topical Chart

Language: Portuguese | Type: Poster | Size: 433kb

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Topical Dosage Form Excipients

Language: Spanish | Type: Data Sheet | Size: 138kb

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Emulsion Reference Guide

Discover the emulsion capabilities, compatibilities and sensory aspects of a range of topical emulsifiers.

Language: English | Type: Brochure | Size: 254kb

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