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Pharmaceutical excipients

Excipients are more than just fillers in a final drug product. They are functional ingredients, providing key benefits such as solubilisation, stabilisation, delivery enhancement, and formulation preservation. Selecting the right ingredient for your formulation ensures that your drug stays stable within your formulation, as well as works the way you need it to. This ultimately translates to improved drug efficacy, extended shelf life, and market success. At the same time, there are additional benefits like increased speed to market, reduced development time, and cost savings from decreased waste in failed batches.
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Croda offers a vast portfolio of excipient solutions, from specialised lipids to high purity specialty chemistries to key functional ingredients which solve challenges faced by pharmaceutical manufacturers and formulators. Don’t see what you need? Get in touch with one of our technical team members to discuss your needs and let’s work together to bring your drug product to market together!
 

Maximise the Performance of Your APIs

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Pharmaceutical solubility guide

As API solubility continues to present challenges for the pharmaceutical formulator, Croda has determined the solubility of a range of actives in a number of Croda’s high purity excipients.

Super Refined™ Excipients

Super Refined™ excipients

Super Refined excipients are stripped of a number of oxidative impurities, such as peroxides, aldehydes, and catalyst residues. The removal of these problematic species helps to reduce negative API & excipient interactions, maintaining both the stability of the drug and the final formulation. In addition, the removal of these impurities can minimise cellular irritation, reduce taste impact, and potentially decrease allergenicity. 

We have a large variety of products, ranging from various polysorbates, polyethylene glycols (PEG), esters, vegetable oils, and more. 

Explore Super Refined™ excipients
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Lipid-based drug delivery technology

Avanti is primarily focused on developing innovative lipid-based products to address specific medical challenges that are not resolved by current technology or drug products.

Controlled release

Controlled release drug delivery systems

Controlled release drug delivery systems are beneficial in both topical and oral dosage forms. Find out how liquid crystal emulsification systems and glycerol mono-oleates can be used for sustained active delivery, resulting in numerous benefits for consumers.

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Penetration enhancement

Our penetration enhancers deliver more of your active pharmaceutical ingredient (API) to the target location in order to improve product efficacy and lower API costs.

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SEDDS and SMEDDS

SEDDS and SMEDDS drug delivery systems are mixtures of oils, surfactants, solvents, and drug substance that rapidly and spontaneously fine oil-in-water emulsions or microemulsions when introduced into aqueous phases under gentle agitation.

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Pharmaceutical solvents

Achieving API solubility is one of the big challenges faced by formulators, with many APIs having low solubility. Our range of Super Refined pharmaceutical solvents can address this challenge, providing a range of polar and non-polar solvents that not only provide solubility, but also excellent stability for APIs.

Let’s work together to bring your drug product to market.